PeakForce QNM is built upon Bruker's PeakForce Tapping mode, which employs peak force for feedback control and oscillates the probe at about 1kHz. The aforementioned limitations are addressed by Bruker with the release of its PeakForce QNM (Quantitative Nanomechanical Property Mapping), which provides better results with respect to speed, resolution, user-friendliness, and quality of delivered information. However, slow acquisition speed and a lack of automated tools have limited the popularity of these techniques. Force spectroscopy and force volume are the conventional techniques used for making quantitative measurement of mechanical forces at the nanometer scale. Tapping mode avoids tip and sample damage caused by friction and shear forces, thus enabling qualitative mechanical property mapping through phase imaging. Although atomic force microscopy is mainly used to produce a 3D profile of the scanned surface, it can provide much more information. Measuring and mapping mechanical properties of live cells is crucial in today's biological research. Sponsored by Bruker Nano Surfaces Aug 27 2013
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